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Discussion Starter · #1 ·
Apparently the USMLE is expanding the amount of immunology on the exam and people taking the test after mid-May will have these changes. Here is the link http://www.usmle.org/General_Information/announcements.aspx?contentId=55 and I also copied the info below. I am honestly not sure how much of a difference these changes make. I would love to hear your thoughts on these, and also how you are studying immunology.

Revised Step 1 Content Outline
In 2009, a subcommittee of the Step 1 Committee began an in-depth review of the Step 1 content outline and the Step 1 item pool. The goals of this group included increasing the number of items in the exam that assess basic science knowledge in a clinical context, an effort that had been underway for several years, as well as a review of the General Principles section of the content outline.
Posted November 02, 2010 [-] Click HERE to close announcement
As a result of the work of this group, the number of items in the examination with non-clinical presentations was reduced; this was announced on April 21, 2010.

At its June 2010 meeting, the Step 1 Committee approved a revised Step 1 content outline. This revision involves recoding items previously included in the General Principles portion of the content outline into Organ System sections of the outline. In addition, items from the General Principles section of the content outline that test immunology were reclassified to a new category, Immune System. This change reflects expansion in the field of immunology.

The updated Step 1 content outline can be viewed here. The previous version of the Step 1 content outline can be viewed here.

Step 1 examinees who expect to test on or after mid-May 2011 may want to become familiar with both the old and the updated content outlines when preparing for their examination.
 

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Thanks for the post!

Thanks for the above post. I looked at those links and Ill just copy and paste the IMMUNE SYSTEM thats added on by the USMLE to the updated Content-

Immune System
Normal processes
• development of cells of the adaptive immune response, including positive and negative selection during
immune development
• structure, production, and function
- granulocytes, natural killer cells, macrophages, mast cells, dendritic cells, cell receptors
- T lymphocytes, including T-lymphocyte receptors, accessory molecules, cell activation and proliferation,
cytotoxic T lymphocytes, and memory T lymphocytes19
- B lymphocytes and plasma cells, including B-lymphocyte receptors, immunoglobulins, cell activation
and proliferation, including development of antibodies and memory B lymphocytes
- structure and function of lymph nodes, host defense mechanisms, host barriers to infection, mucosal
immunity
- immunogenetics
- Rh and ABO antigens, including genetics
• cellular basis of the immune response and immunologic mediators
- antigen processing and presentation in the context of MHC I and MHC II molecules, including
distribution of MHC I and MHC II on different cells, mechanism of MHC I and MHC II deficiencies,
and the genetics of MHC
- regulation of the adaptive immune response
- activation, function, and molecular biology of complement
- function and molecular biology of cytokines
• basis of immunologic diagnosis
Abnormal processes
• disorders with alterations in immunologic function
- abnormalities in adaptive immune responses
- deficiencies of phagocytic cells and natural killer cells
- complement deficiency
- HIV infection/AIDS
- Non-HIV infections of lymphocytes
- systemic diseases of immunologic function
- systemic disorders affecting the immune system and the effect of age on the function of components of
the immune system
• immunologically mediated disorders
- type I, type II, type III hypersensitivity
- type IV hypersensitivity
- transplantation risks and rejection, including transfusion reactions
- isoimmunization, hemolytic disease of the newborn
• drug-induced adverse effects on the immune system, including Jarisch-Herxheimer
Principles of therapeutics
• mechanisms of action and use of drugs that specifically affect immune function
- vaccines (active and passive)
- antiretrovirals
- immunomodulating and antineoplastic drugs
- biologics, including monoclonal and polyclonal antibodies
• other therapeutic modalities
Gender, ethnic, and behavioral considerations affecting disease treatment and prevention, including psychosocial,
cultural, occupational, and environmental
• emotional and behavioral factors
• influence on person, family, and society
• occupational and other environmental risk factors
• gender and ethnic factors
 

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i think they already started immuno questions as experiments as i had ALOT of immuno questions some really hard, and some were okay in difficulty....

so they're testing the immuno questions as experimentals right now till they implant the good questions in may.
 

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i think they already started immuno questions as experiments as i had ALOT of immuno questions some really hard, and some were okay in difficulty....

so they're testing the immuno questions as experimentals right now till they implant the good questions in may.
Yes some of my friends took the exam recently and also said immuno was heavily tested..but yeah I think you are right..they are being used as experimental right now!

But Im hoping this is on or after mid may = May 15!
 

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I really dont see any reason to panic becuase the above listed topics are covered by KLN anyways, so we already know it. Only thing is, before we weren't tested on it.. now we are! :notsure:
 

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Discussion Starter · #7 ·
I really dont see any reason to panic becuase the above listed topics are covered by KLN anyways, so we already know it. Only thing is, before we weren't tested on it.. now we are! :notsure:
Yeah and now we need to understand it in a more clinical context...
 

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need to know the change

hi
can anyone tell me there is anything new topic other than given in kaplan and please also tell me the reference to a good book for those new extra kaplan added topics. thanks in advance
 
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