Guys I have a question here regarding Chron's and oxalate kidney stones.
I learned that in chron's due to the inflammation of the wall of terminal ileum you cannot absorbe bile acids and therefore you will have malabsorption and therefore lipids in the bowel are going to bind to calcium from diet.
Normally calcium from diet binds oxalate from diet and enables oxalate excretion in the feces. Since calcium is binding to lipids in Chron's, oxalate is going to be reabsorbed and in the kidneys it will form oxalate stones.
Now here is my question, when you take orlistat basically you are inducing a fat malabsorption. Based on what I explain above is it possible that Orlistat can cause oxalate kidney stones??????????
I learned that in chron's due to the inflammation of the wall of terminal ileum you cannot absorbe bile acids and therefore you will have malabsorption and therefore lipids in the bowel are going to bind to calcium from diet.
Normally calcium from diet binds oxalate from diet and enables oxalate excretion in the feces. Since calcium is binding to lipids in Chron's, oxalate is going to be reabsorbed and in the kidneys it will form oxalate stones.
Now here is my question, when you take orlistat basically you are inducing a fat malabsorption. Based on what I explain above is it possible that Orlistat can cause oxalate kidney stones??????????
