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Discussion Starter · #1 ·
A 73 year old woman presented with left sided lower abdominal discomfort and a pelvic mass on examination. Surgery was and a mass has been removed (picture below). Histopathology confirmed a benign ovarian tumor. What is the most likely classification of this ovarian tumor?

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A- Epithelial surface tumor
B- Germ cell tumor
D- Stromal tumor
E- Metastatic tumor
F- Krukenburg tumor
 

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Epithelial surface tumor is the "classical" ovarian adenocarcinoma subtype & it is malignant, of course. Metastatic tumors are malignant by definition, whilst Krukenberg tumor is a special form of tumor metastatic to the ovary, deriving from the stomach (signet-ring cells are characteristic), and rarely from other GI locations or even the breast.

Germ cell tumors (eg dysgerminoma) are malignant tumors & are expected in younger populations of women, rather than postmenopausal women.

What is more, the macroscopic image of this tumor reveals a solid tumor, consisting of fibrous, pale-yellow tissue.

According to the above, I would chose D - stromal cell tumor, and more specifically thecoma (in order to differentiate it from granulosa cell tumor, which is also a stromal cell tumor, with a probability of 20% to be malignant, microscopically characterized by the so-called Call-Exner bodies).
 

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