[Sabio]

You might face a case in which there's a rash in the palms and soles, what diagnoses that you should be thinking of for the USMLE?

Here's the list

• Secondary and Congenital Syphilis with it's characteristic Copper colored rash.
• Rocky Mountain Spotted Fever (specially on the wrists) and also Typhus.
• Hand, Foot, and Mouth Disease caused by Coxsackie A virus.
• Kawasaki, Measles, or Toxic Shock Syndrome (all peeling rashes).
• Meningococcemia may cause petichiae on the palms and soles.
• Bacterial endocarditis with it's Janeway lesions and Osler's nodes.
• Tylosis (risk of esophageal carcinoma)
• Keratoderma blenorrhagica (Reiter's syndrome)
• Graft Versus Host Disease rash.

 

[indian]

Probably we can add Acral lentiginous melanoma to the list

 

[tamta]

acute HIV

You might face a case in which there's a rash in the palms and soles, what diagnoses that you should be thinking of for the USMLE?

Here's the list

• Secondary and Congenital Syphilis with it's characteristic Copper colored rash.
• Rocky Mountain Spotted Fever (specially on the wrists) and also Typhus.
• Hand, Foot, and Mouth Disease caused by Coxsackie A virus.
• Kawasaki, Measles, or Toxic Shock Syndrome (all peeling rashes).
• Meningococcemia may cause petichiae on the palms and soles.
• Bacterial endocarditis with it's Janeway lesions and Osler's nodes.
• Tylosis (risk of esophageal carcinoma)
• Keratoderma blenorrhagica (Reiter's syndrome)
• Graft Versus Host Disease rash.

Acute HIV rash may involve palms and soles

 

[Boleyut]

That was an really impressive post and i like that.

 

[sanjana bhimani]

thanks for sharing the list

 

[Asia]

Sorry I beg to differ minutely

Dear author, you did a great compilation .I differ with you minutely .Not undermining your hard work at all . I am of the opinion that
Typhus in itself does not present as palm ,soles, face rash .
How do we clinically differentiate between Rickettsia and Typhus then ?
It is by the appearance of the rash :
Rickettsia rickettsi (RMSF) first appears in wrists and ankles ,spreads centrally towards the trunk ,involving palms and soles.
Rickettsia typhi/prowazeki (endemic/epidemic TYPHUS) first appears in the trunk and spreads out sparing palms and soles.
Hence Typhus is not a d/d for palm and sole rash .
Please correct me if I am wrong with reference .My reference is FA2015

 

[chevelle]

Thank you for this!!!

 

[Studyqueen]

YEs!!!

Thank you ever so much