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Discussion Starter #1 (Edited)
You might face a case in which there's a rash in the palms and soles, what diagnoses that you should be thinking of for the USMLE?

Here's the list

  • Secondary and Congenital Syphilis with it's characteristic Copper colored rash.
  • Rocky Mountain Spotted Fever (specially on the wrists) and also Typhus.
  • Hand, Foot, and Mouth Disease caused by Coxsackie A virus.
  • Kawasaki, Measles, or Toxic Shock Syndrome (all peeling rashes).
  • Meningococcemia may cause petichiae on the palms and soles.
  • Bacterial endocarditis with it's Janeway lesions and Osler's nodes.
  • Tylosis (risk of esophageal carcinoma)
  • Keratoderma blenorrhagica (Reiter's syndrome)
  • Graft Versus Host Disease rash.
 

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acute HIV

You might face a case in which there's a rash in the palms and soles, what diagnoses that you should be thinking of for the USMLE?

Here's the list

  • Secondary and Congenital Syphilis with it's characteristic Copper colored rash.
  • Rocky Mountain Spotted Fever (specially on the wrists) and also Typhus.
  • Hand, Foot, and Mouth Disease caused by Coxsackie A virus.
  • Kawasaki, Measles, or Toxic Shock Syndrome (all peeling rashes).
  • Meningococcemia may cause petichiae on the palms and soles.
  • Bacterial endocarditis with it's Janeway lesions and Osler's nodes.
  • Tylosis (risk of esophageal carcinoma)
  • Keratoderma blenorrhagica (Reiter's syndrome)
  • Graft Versus Host Disease rash.
Acute HIV rash may involve palms and soles
 

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Sorry I beg to differ minutely

Dear author, you did a great compilation .I differ with you minutely .Not undermining your hard work at all . I am of the opinion that
Typhus in itself does not present as palm ,soles, face rash .
How do we clinically differentiate between Rickettsia and Typhus then ?
It is by the appearance of the rash :
Rickettsia rickettsi (RMSF) first appears in wrists and ankles ,spreads centrally towards the trunk ,involving palms and soles.
Rickettsia typhi/prowazeki (endemic/epidemic TYPHUS) first appears in the trunk and spreads out sparing palms and soles.
Hence Typhus is not a d/d for palm and sole rash .
Please correct me if I am wrong with reference .My reference is FA2015
 
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