In menopause, you still have some estrogen although it's reduced compared to its premenopausal levels.Why women have endometrial cancer in the menopause?
I believe that the have less estrogen!
or it can be due to hormone replacement therapy and more estrogen in dat....In menopause, you still have some estrogen although it's reduced compared to its premenopausal levels.
The source of postmenopausal estrogen is the adrenal zona reticularis where DHEA is produced and then aromatized in ovarian stroma and fatty tissues to Estrone.
It's the effect of unopposed estrone (as no more progesterone from corpus letuem) that causes endometrial hyperplasia which is a precursor of endometrial carcinoma, the most common female genital cancer in the aging US population and the second killer after ovarian cancer.
TO much cycles of menstruation. like early menarche or late menopause!!Why women have endometrial cancer in the menopause?
I believe that the have less estrogen!
thanks for explainingIn menopause, you still have some estrogen although it's reduced compared to its premenopausal levels.
The source of postmenopausal estrogen is the adrenal zona reticularis where DHEA is produced and then aromatized in ovarian stroma and fatty tissues to Estrone.
It's the effect of unopposed estrone (as no more progesterone from corpus letuem) that causes endometrial hyperplasia which is a precursor of endometrial carcinoma, the most common female genital cancer in the aging US population and the second killer after ovarian cancer.