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Yes
In USMLE exam
If you have high renin then think primary
If you have low renin then think secondary hyperaldosteronism
 

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Yes the answer is:
- primary hyperaldosteronism (Conn's syndrome) = low renin
Caused by adrenal adenoma mostly, do CT for abdomen.

- secondary hyperaldosteronism = high renin
More common than primary, and related to hypertension (renal artery stenosis) and edematous disorders (CHF, nephrotic, cirrhosis).
 

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Discussion Starter · #5 ·
negative feedback

Yes if you consider negative feedback, the inverse relationship between aldosterone secretion and renin levels would be the correct choice.
 

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difference between primary and secondary hyperaldosteronism

:)
The following article says that more stringent criteria are necessary to diagnose primary hyperaldosternism. What about just for differentiation between primary and secondary hyperaldosteronism? Would renin levels be sufficient there? :notsure:
http://emedicine.medscape.com/article/117280-diagnosis

Thanks so much in advance!
primary is due to adenoma in zona glomerulosa lab findings hypernatremia hypoklemiametabolic alkalosisand associated hypertensionplasma renin is dec in secondary hyperaldosteronism plasma renin activity increase dec renal bd flow activates the renin angiotensin aldosterone system it is compensatory reaction to dec cardic out put
 
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