[bronchiole]

In my understanding, if vessel compliance is increased, diastolic BP should decrease.
but in Kaplan notes, both 2008 and 10 version, they say, in case of pulse pressure, decreased vessel compliance = decreased diastolic BP.

kinda confused here. what am I missing?

plus, if anyone of you have Kaplan 2008 errata....please help me here with that.

thank you.

 

[doctorsmonsters]

ok I'll try to break it down for you.

If a vessel is compliant, it means that volume changes cause less changes in pressure. If a vessel is less compliant, volume changes would cause a greater change in pressure. So in a less compliant vessel, during diastole when the volume decreases, the pressure drop is also greater and we get a lower diastolic pressure.

In mathematical terms, compliance= change in volume/change in pressure

If change in volume is constant, compliance is inversely proportional to change in pressure. So if a vessel is less compliant, the change in pressure (or drop in pressure in case of diastole) is larger.

 

[bronchiole]

First of all, thanks for your time.

I don't have any problem understanding that. I mentioned that in my post. I am just confused when they are mentioning pulse pressure ,they are saying the exact opposite of what you/I said and that is in both editions. Hence, my confusion.


but according to your explanation, if I consider pulse pressure,
pressure change (systole has to increase and diastole has to decrease) increased and volume change is constant, only then i can think that decreased vessel compliance comes with decreased diastolic.

Please give a response on it.

btw,u made a good explanation.

 

[doctorsmonsters]

OK I am not sure I understood your question but if I did, you got it right.

Pulse pressure= systolic pressure-diastolic pressure

So decreased compliance will lead to high systolic and low diastolic, means large difference and large pulse pressure.

 

[Mondoshawan]

In my understanding, if vessel compliance is increased, diastolic BP should decrease.

I think this is where you're backwards.

What doctorsmonters wrote is correct: a fixed stroke volume going into a vessel with decreased compliance results in a greater pulse pressure - that is to say, a greater gap between systolic and diastolic pressures. Systolic pressure goes up with decreased compliance and diastolic goes down.

hope that helps?

 

[bronchiole]

I think this is where you're backwards.

What doctorsmonters wrote is correct: a fixed stroke volume going into a vessel with decreased compliance results in a greater pulse pressure - that is to say, a greater gap between systolic and diastolic pressures. Systolic pressure goes up with decreased compliance and diastolic goes down.

hope that helps?

yeah,that is exactly what I said in my 2nd post.thanks for your input.

 

[bronchiole]

OK I am not sure I understood your question but if I did, you got it right.

Pulse pressure= systolic pressure-diastolic pressure

So decreased compliance will lead to high systolic and low diastolic, means large difference and large pulse pressure.

thanks a lot.I am glad that it is now clear to me.thank you sooo much.:happy:

 

[doctorsmonsters]

I'm glad too!

 

[drcuddles]

Thanks for your explanations mentioned above, it really helped. But can someone help me apply those rules into valvular disease !

What is the mechanism behind wide pulse pressure in Aortic Regurgitation and narrow pulse pressure in Aortic stenosis ?

Aren't Both supposed to have wide (high) pulse pressure because in case of Aortic stenosis systolic pressure increases and diastolic pressure decreases, while in case of regurgitation diastolic pressure decreases due to less blood volume.