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A 4-year-old male with mental retardation, self-mutilation, and hyperuricemia is likely to have a de

  • Breakdown of branched-chain amino acids

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  • Conversion of homogentisic acid to methylacetoacetate

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  • Degradation of galactocerebroside

    Votes: 0 0.0%
  • Recycling of guanine and hypoxanthine

    Votes: 3 100.0%
  • Synthesis of UMP and CTP

    Votes: 0 0.0%
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Discussion Starter · #1 ·
A 4-year-old male with mental retardation, self-mutilation, and hyperuricemia is likely to have a deficiency of an enzyme involved in which of the following processes?

A. Breakdown of branched-chain amino acids
B. Conversion of homogentisic acid to methylacetoacetate
C. Degradation of galactocerebroside
D. Recycling of guanine and hypoxanthine
E. Synthesis of UMP and CTP

It's from Step1Daily.
 

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A 4-year-old male with mental retardation, self-mutilation, and hyperuricemia is likely to have a deficiency of an enzyme involved in which of the following processes?

A. Breakdown of branched-chain amino acids
B. Conversion of homogentisic acid to methylacetoacetate
C. Degradation of galactocerebroside
D. Recycling of guanine and hypoxanthine
E. Synthesis of UMP and CTP

It's from Step1Daily.
D. that is patient with lesch nyhan syndrome HGPRT: Hyperuricemia, gout, pissed of (self mutilation), retardation, DYstonia.
 

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Lesch Nyhan syndrome sounds about right

As an aside, im surprised how many biochem applications the step 1 has. Even a lot of the patho questions had me thinking back to my days of reading lippincott biochem :p
 
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