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Hey guys, I was reading up on Nephritic Glomerular dz's in Rapid Review path and for IgA glomerulopathy (Berger's dz) i noticed it says its due to: "Increased mucosal synthesis and DECREASED CLEARANCE OF IgA; INCREASED SERUM IgA"
when I looked up IgA glomerulopathy in First Aid 2010, it's says its due to "INCREASED SYNTHESIS OF IgA"
... i'm confused... is IgA synthesis increased b/c the IgA is getting trapped in the mesangial cells of the kidney which are then being destroyed by anti-bodies, hence decreased clearance????
when I looked up IgA glomerulopathy in First Aid 2010, it's says its due to "INCREASED SYNTHESIS OF IgA"
... i'm confused... is IgA synthesis increased b/c the IgA is getting trapped in the mesangial cells of the kidney which are then being destroyed by anti-bodies, hence decreased clearance????
