[insanity]

Can someone please explain this?

 

[Mondoshawan]

I know of two effects:

• plasmin cleaves C2b into kinin
• I think plasmin can activate C3

Anyone else know of any? It seems like all those serine proteases are sort of promiscous, and it seems hard to keep track of who can do what to whom... :scared:

 

[doc_study]

Plasmin also cleaves C5 to C5a.. (major chemo attractant for neutrophils)