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Sequence-specific cleavage of proteins plays a role in which of the following processes?

A) Activation of G proteins by hormone receptors
B) Assembly of microtubules
C) Cellular uptake of iron
D) Initiation of coagulation
E) Transport of proteins into the nucleus
 

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I think the correct answer is D. Throughout the coagulation cascade, every factor constitutes a substrate ready to be cleaved by the previous factor, once activated. Coagulation factors are mainly serine proteases.

A is related to successive phosphorylations.

B is related to polymerization-depolymerization of tubulins.

C is related to Fe binding to proteins (transferrin & ferroportin).

E is related to nuclear pore complexes, importins etc.
 
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