A. 75 mg every 3 hours

B. 75 mg every 6 hours

C. 75 mg every 9 hours

D. 100 mg every 3 hours

E. 100 mg every 6 hours

F. 100 mg every 12 hours

1 - 10 of 10 Posts

A. 75 mg every 3 hours

B. 75 mg every 6 hours

C. 75 mg every 9 hours

D. 100 mg every 3 hours

E. 100 mg every 6 hours

F. 100 mg every 12 hours

Joined

·
109 Posts

note :

maintainance dose = clearance X steady state conc. X dosing interval

so if clearance is reduced to half (in older ppl) then maintainance dose shud be reduced to half (provided that dosing interval is constant) to reach the same steady state conc.

note here only 50% of drug is excreted by kidney, so dose reduction shud be of only renally excreted drug that is 50mg , now resdution of 50 to half 25+50(excreted by liver) = 75 mg.....

so 75 mg after every 6 hours

Very good... I like your explanation.

note :

maintainance dose = clearance X steady state conc. X dosing interval

so if clearance is reduced to half (in older ppl) then maintainance dose shud be reduced to half (provided that dosing interval is constant) to reach the same steady state conc.

note here only 50% of drug is excreted by kidney, so dose reduction shud be of only renally excreted drug that is 50mg , now resdution of 50 to half 25+50(excreted by liver) = 75 mg.....

so 75 mg after every 6 hours

So I was wondering.. what is the prevalence of mathematical type questions? I suck at it, and tbh will screw up no matter how well prepared I am for them :toosad:

Joined

·
335 Posts

Well, not only this question.

I meant other question in general that DO require equations etc.

Joined

·
335 Posts

That's right, it's not all about solving an equation and doing numbers. It's all about understanding the concept. I did so many physio and biostat qns by using the concepts. But I recommend you to do some practice qns on that particular subjects so you will not panic on the exam....haha, of course! and it wasn't in response to your post, I am pretty bad at all the equations and stuff myself, so when I saw the question, I tried to solve it without going through the pain of trying to recall the equation. )

Im not really a math person, I absoleutly hate it.. I hated all the equations and stuff uptill now (biostats, pharm & patho mostly - yet to do physio)

So I was wondering.. what is the prevalence of mathematical type questions? I suck at it, and tbh will screw up no matter how well prepared I am for them

No!!! it's B) 75 mg every 6 hourswats the correct ans i gess its c 75mg in 9hrs

1 - 10 of 10 Posts

Join the discussion

USMLE Forums

A forum community dedicated to the United States Medical Licensing Examination. Come join the discussion about schools, exams, news, prep, reviews, accessories, classifieds, and more!

Full Forum Listing
Recommended Communities

Join now to ask and comment!