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Diffuse systemic sclerosis- kidney, heart , musculoskeletal involvement which are usually absent in limited disease + anti-topoisomerase -+ve

Limited syst sclerosis -CREST SYNDROME ; anti-centromere ab +ve
 

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Discussion Starter · #3 ·
what is scleroderma.. i mean where is restrictive lung disease more common limited or diffuse? what about the rash distribution?
 

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what is scleroderma.. i mean where is restrictive lung disease more common limited or diffuse? what about the rash distribution?
lung is more common and seen only in diffuse. limited will show only crest symptoms, i.e., C-calcinocis, R-raynaud , Esophageal dysmotility, Sclerodactaly, T telengectasia,
Rash? I am not sure if there is rash in either of these.
 
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