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A 21-year-old man is brought to the emergency department 15 minutes after being hit by a speeding motorist while crossing the street. Lower extremity x-rays show multiple fractures of both femurs. Seventy-two hours later, he complains of shortness of breath. He is tachypneic and hypoxic. He does not respond to oxygen therapy, and a chest x-ray shows patchy bilateral infiltrates. Which of the following cells play a crucial role in the pathogenesis of this process?
A. CD4-positive lymphocytes
B. CD8-positive lymphocytes
C. Eosinophils
D. Mast cells
E. Neutrophils
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