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A 12-year-old boy is brought to his pediatrician by his mother with a two-day history of tea-colored urine. He recently completed a five-day course of penicillin for Streptococcal pharyngitis. His blood pressure is elevated. He has periorbital edema. Which of the following is the most likely microscopic renal lesion?

A. Basement membrane immune complex deposition
B. Basement membrane thickening
C. Foot process effacement
D. Mesangial proliferation
E. Subepithelial immune complex deposition
 

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E (Lumpy-Bumpy)

This is a case of post-strep Glomurelonephritis, so the answer is E.

PSGN is usually characterised by granular deposits of IgG/M and C3 in the glomerulus. Characteristic is "Sub-epithelial Humps"
 
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