A 19-year-old male presents to the student health service after his roommate noted a yellowish discoloration to his skin while up late studying for an exam. After a meal and several hours sleep, the discoloration resolved. Laboratory tests are obtained, ALT 25 U/dL, AST 20 U/dL, Bilirubin (direct) 0.8 mg/dL, Bilirubin (total) 2.5 mg/dL. Which of the following is responsible for this patient’s disease?
A- Canalicular cholestasis
B- Decreased activity of glucuronyl transferase
C- Impaired transport of bilirubin into the bile canaliculus
D- Impaired uptake of circulating bilirubin
E- Immune hemolysis
A- Canalicular cholestasis
B- Decreased activity of glucuronyl transferase
C- Impaired transport of bilirubin into the bile canaliculus
D- Impaired uptake of circulating bilirubin
E- Immune hemolysis