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A patient with hypertension, hypernatremia, hypokalemia, and increased edema is found to have an aldosterone-producing adrenocortical adenoma. Serum measurement of renin in this patient will be:

A. Same as an individual with secondary hyperaldosteronism
B. Higher than an individual with secondary hyperaldosteronism
C. There is no consistent renin level correlation between primary and secondary hyperaldosteronism
D. Less than an individual with secondary hyperaldosteronism
E. None of the above
 

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D. Less than an individual with secondary hyperaldosteronism.

Primary excess aldosterone would exert a negative feedback on renin, leading to low renin levels in serum. In secondary hyperaldosteronism, the primary initiating pathology is excess renin which causes excess release of aldosterone.
 
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