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Discussion Starter · #1 ·
Can someone please explain why TIBC increases in pregnancy and OCP use while % transferring saturation decreases?

thanks in advance.
 

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Can someone please explain why TIBC increases in pregnancy and OCP use while % transferring saturation decreases?

thanks in advance.
Your body needs more iron in pregnancy to make more hemoglobin etc and some ppl develop iron deficiency anemia, ( it can also happen if ur pre pregnancy iron stores were at the lower scale of normal)

like all causes of iron def anemia, ferritin goes down, TIBC increases (low ferritin causes transferrin to increase) because there are more sites on transferrin to bind iron so its capacity is increased in low iron states. And % sat of transferrin decreases because transferrin is not saturated with enough iron .
 

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Discussion Starter · #3 ·
Your body needs more iron in pregnancy to make more hemoglobin etc and some ppl develop iron deficiency anemia, ( it can also happen if ur pre pregnancy iron stores were at the lower scale of normal)

like all causes of iron def anemia, ferritin goes down, TIBC increases (low ferritin causes transferrin to increase) because there are more sites on transferrin to bind iron so its capacity is increased in low iron states. And % sat of transferrin decreases because transferrin is not saturated with enough iron .
Thank you for the reply. What about OCPs, any idea how it brings about these lab values?

thank you
 
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