[usmleguy]

Here's few high yield points about Tourette syndrome:

• It is associated with decreased dopamine in caudate nucleus.
• There's a genetic relationship with ADHD and obsessive compulsive disorder.
• Haloperidol and other antipsychotics useful for treatment.

 

[patient doctor]

The association with decreased dopamine doesn't make sense because the treatment is to block dopamine. Maybe it is associated with increased dopamine?

 

[Evergreen]

Point

The association with decreased dopamine doesn't make sense because the treatment is to block dopamine. Maybe it is associated with increased dopamine?

In High-Yield Behavioral Science, Table 9-3, it is mentioned that Tourette syndrome is associated with decreased serotoin metabolites such as 5-HIAA.

 

[husseinalaa]

Patients with TS have increased density of the presynaptic dopamine transporter and an increased density of postsynaptic D2 dopamine receptors, suggesting increased uptake and release of dopamine.Happy-2

 

[Dr Jones]

really?

:sorry:
Tell me more

Patients with TS have increased density of the presynaptic dopamine transporter and an increased density of postsynaptic D2 dopamine receptors, suggesting increased uptake and release of dopamine.Happy-2