A chemotherapeutic agent classified as a guanosine derivative demonstrates significant antiviral activity against herpes simplexvirus type 1 herpes simplexvirus type 2, and varicella zoster virus. The same agent demonstrates weak antiviral activity against Epstein-Barr virus and cytomegaly virus. Which of the following best explains this difference in viral susceptibility to the drug?
A. Viral protease activity
B. DNA polymerase structure
C. Structural protein composition
D. Drug phosphorylation rate
E. Drug degradation rate
A. Viral protease activity
B. DNA polymerase structure
C. Structural protein composition
D. Drug phosphorylation rate
E. Drug degradation rate