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VJ and VDJ

3420 Views 0 Replies 1 Participant Last post by  rasheed
The DNA rearrangements that is responsible for the diversity of the lymphocyte receptor specificity and idiotypic antigenicity produced by the V, D, and J DNA segments.
Always forgetting which is which? Here's a mnemonic
VDJ = more genes = Bigger (heavy) chain of the immunoglobuline variable redgion and Beta chain of the TCR
VJ = less genes = light chain of the immunoglobuline = alpha chain of the TCR

Hope that helps
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