Which antibiotic caused this clinical picture?

7202 Views 7 Replies 6 Participants Last post by Oncology_freak, Feb 27, 2014

Taiyakikung

Discussion Starter · Feb 27, 2011

A patient is being treated with an antibiotic for a vancomycin resistant enterococcal infection. He consumes an over the counter medication containing ephedrine and develop a significant spike of blood pressure that leads to a pounding headache. He is transported to the hospital. As part of the workup, blood tests indicate some bone marrow suppression. Which of the following antibiotics is most likely associated with this clinical picture?

A. Azithromycin
B. Ciprofloxacin
C. Erythromycin Estolate
D. Gentamicin
E. Linezolid

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doctorsmonsters

· #2 · Feb 27, 2011

I am probably wrong but for some reason Ciprofloxacin rings a bell.

)

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doctorsmonsters

· #4 · Feb 27, 2011

aktorque said:
Hmm... tough one!

I know that chloramphenicol known to cause bone marrow suppression, it's not given as a choice here.

Next I'd say penicillin family can cause BMS eg. Piperacillin - not on the list

Linezolid can cause BMS by MOA UNKNOWN

You are right!!!! Linezolid it is.

http://en.wikipedia.org/wiki/Linezolid

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