Which enzyme deficiency causing this hemolytic anemia?

E

Hemolytic anemia in AR is PK deficiency !

oh.... i tot it was C.

i guess u're prolly ryte.

E is the correct answer). Only two enzymes of those
listed in the answer choices specifically cause hemolytic anemiayruvate kinase and glucose-6-phosphate dehydrogenase.G6PDdeficiency is inherited as an X-linked recessive trait, so females would not be affected.pyruvate kinase deficiency is an AR disorder,affecting males and females approximately equally. If this enzyme is deficient, red cells have trouble producing enough ATP to maintain the Na+/K+ pump on the plasma membrane, secondarily causing swelling and lysis.

your answer is rather confusing. The questions states that two sisters have hemolytic anemia, and you state that G6PD is the answer although "as an X-linked recessive trait, so females would not be affected." So how can the answer be C??

No he did not say that

HouseWannabe said:

your answer is rather confusing. The questions states that two sisters have hemolytic anemia, and you state that G6PD is the answer although "as an X-linked recessive trait, so females would not be affected." So how can the answer be C??

Click to expand...

He did not say G6PD is the answer. He said Pyruvate Kinase deficiency is the answer.

13monument said:

He did not say G6PD is the answer. He said Pyruvate Kinase deficiency is the answer.

Click to expand...

samo1 said "Yes .C is the correct answer)"

HouseWannabe said:

your answer is rather confusing. The questions states that two sisters have hemolytic anemia, and you state that G6PD is the answer although "as an X-linked recessive trait, so females would not be affected." So how can the answer be C??

Click to expand...

E is correct.i made a mistake on writing.i corrected it.Thanks

thx sam

the explanation was good. i realize this question has been asked before in the kaplan q-bank but i always forget this one.

i remember now. AR is PK def and X-linked G6PDH def!