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Discussion Starter · #1 ·
During class in kaplan , paediatric prof asked this ques to get some idea ...

In winter season a 20 months baby presents with high fever for 7 days with bilateral conjunctivitis without exudate with erythema in hand and feet , strawberry tongue , trunk rash and inflammation of cervical node , the baby has given most appropriate drug for this condition , but he is in a risk of developing hyperammonemia and cerebral edema and may become comatous .... which vaccine below if given in this pt may prevent those adverse effect of drug ... If possible please ans why u think so ....

1. pmeumococci
2. hemophilus
3. meningococci
4. MMR
5. influenza
 

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This question seems to be incoherent because it's not clear which is causing the cerebral edema, is it the disease or is it the drug given
Also the case description goes with Kawasaki syndrome and non of it's treatment cause such complication and none of the vaccines prevent it.
If he's thinking about scarlet fever (which is wrong coz it does not cause this prolonged fever) then again non of the vaccines mentioned is preventative
Send my regards to your teacher
 

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Discussion Starter · #3 ·
Yes may be my ques was not as correct as that prof said ... sorry for that
Its kawasaki disease , of course not , its complication does not cause such disease , but the main point here is winter season , as in kawasaki disease high dose of aspirin we give , so baby have chance of reye syndrome which is characterized by encephalopathy , cerebral edema if he get influenza in that winter season too with kawasaki .... What the main point is ... if its winter season its better to give flu vaccine ......
 

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Flu is not mentioned!

Yes may be my ques was not as correct as that prof said ... sorry for that
Its kawasaki disease , of course not , its complication does not cause such disease , but the main point here is winter season , as in kawasaki disease high dose of aspirin we give , so baby have chance of reye syndrome which is characterized by encephalopathy , cerebral edema if he get influenza in that winter season too with kawasaki .... What the main point is ... if its winter season its better to give flu vaccine ......
OK, now I understand.
But flu vaccine is not mentioned in the options!
 

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Are you kidding...

hemophilus is the influenza vaccine.
You need to seriously review your microbiology.
Influenza is a virus, Hemophilus influenzae is a bacterium.
Reye syndrome develops in children who are infected with a virus (usually influenza or chicken pox) and take Aspirin. There's no risk of Reye syndrome in children who are infected with Hemophilus influenzae.
 

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Discussion Starter · #7 ·
Yes i should put flu vaccine there ... its my mistake for that ....
Yes reye syndrome always associated with varicella and influenza
 

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Thank you YoramFishke for your polite reminder that I need to review my micro, good think that I wrote my step and aced it so no review needed just yet.

yes I realize that haemophilus is a bacteria, and that it's not a virus; however if you've read the coating for the influenza vaccine is made from bacterial capsules not viruses.

Also, In infants and young children, H. influenzae type b (Hib) causes bacteremia, pneumonia, and acute bacterial meningitis. What I was trying to say is that Hamophilus is Hib.

This isn't the cause of the influenza pandemic but it's termed haemophilus influenza. Hope I've explained myself enough so to not warrant anymore unneeded criticism.
 

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Still off the point!

Thank you YoramFishke for your polite reminder that I need to review my micro, good think that I wrote my step and aced it so no review needed just yet.

yes I realize that haemophilus is a bacteria, and that it's not a virus; however if you've read the coating for the influenza vaccine is made from bacterial capsules not viruses.

Also, In infants and young children, H. influenzae type b (Hib) causes bacteremia, pneumonia, and acute bacterial meningitis. What I was trying to say is that Hamophilus is Hib.

This isn't the cause of the influenza pandemic but it's termed haemophilus influenza. Hope I've explained myself enough so to not warrant anymore unneeded criticism.
You are off the point my dear,
Even if the influenza vaccine is coated with bacterial capsules it's still named Influenza vaccine not hemophilus influenzae vaccine.
Giving Hib does not by any means prevent the development of Reye syndrome.
I apologize if hurt your feelings :rolleyes:
 

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Discussion Starter · #10 ·
Check it out guys ..... i hope now THE QUES is okhe .... we are here for discussion ... and of course TO ERR IS HUMAN .....
 

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According to USMLERx, you can give the MMR (measles) vaccine to an infant and prevent a future complication called Pan Sclerosing Encephalitis, 10, 12, 13+ years down the road.

Its been more than 2 months since I read that, but I think thats true. Unless I'm making it up on accident.
 

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According to USMLERx, you can give the MMR (measles) vaccine to an infant and prevent a future complication called Pan Sclerosing Encephalitis, 10, 12, 13+ years down the road.

Its been more than 2 months since I read that, but I think thats true. Unless I'm making it up on accident.
Yes, MMR will prevent SPE but it will not prevent Reye syndrome!
 

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Whats the debate for?

I can see the option of INfluenza vaccine in the question.
Why are you all discussing Hemophilus vaccine. Flu vaccine is same as Influenza(virus) vaccine so acc to Professor Influenza vaccine shud prevent cerebral edema. But m confused why kawasaki is there in the picture ? Is it to bring aspirin in focus?
 

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1. Aspirin is the only (?) used in Kawasaki disease in children and surprisingly does not cause Reye's syndrome in such patients!!

2. Patients with Kawasaki disease is usually treated also with Ig...and when ever Immunoglobin is given, live vaccines are CI!! Hence, the above arguments u ppl were making does not apply!

Thank u
 
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