LCAD - long chain fatty acyl coA dehydrogenase MCAD - medium chain fatty acyl coA dehydrogenase SCAD - small chain fatty acyl coA dehydrogenase
They are used in the Beta Oxidation reaction in the Mitochondrial Matrix. There names are so because each of them are used for a different lengths of Fatty Acids. LCAD for fatty acids with more than 10 Carbon chains, MCAD for 8 to 10 carbon chains and SCAD to finish the job with less than 7 carbon chains.
The deficiency causes Fasting Hypoglycemia and hypoketosis (since no ketone bodies are produced). Other symptoms include: lethargy, vomiting, coma, and death. It is Autosomal Recessive with variable expression.
Also, note that since this is occurring in a fasting stage the body then utilizes Omega Oxidation (methyl carbon oxidation) from Peroxisomes to generate energy which produces Dicarboxylic Acid. Therefore, you will also see dicarboxyacedmia in the blood work.
The primary treatment is IV Glucose.
Prevention is frequent feeding, high-carbohydrate and low-fat diet.