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wt ive learnt from goljan patho
after first xposure there is stimulation of Th2 cells tht secrete leukotrienes.
of them IL 5 stimulates proliferation n maturation of eosinophils tht then secrete major basic proteins for activation of mast cells, chemotactic factor A n also enzyme peroxidase tht generates O2 radicals n kill the target cells
so! u c eosinophilia in allergy due to IL5))))))
 
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