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actually the answer is in histology.
mast cells and basophils...and granulocytes....so they granulate in response to FC portions of antibodies cross linkages.
The granules secreate excessive amounts of the inflammotory promoter HISTAMINE...
SO...there has to be something to deactivate the HISTAMNE....
HISTAMINASES are present in the granules of EIOSINOPHIlic granules.
hence in Allergy, and hypersensitvity...eiosinophils are active to counteract and limit the inflamation, in this case.so eiosinophil s persist in such patients even if they are no in active allery or asthma...etc...
you can check this in whethers, the atlas...they have cool micrographs...
let me know if youre not clear...
 
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