An 18-year-old man is evaluated for possible immunodeficiency disease because of a lifelong history of chronic lung infections, recurrent otitis media, and multiple episodes of bacterial meningitis. Serum immunoglobulin levels are as follows: IgM 300 mg/dL, IgG 660 mg/dL, IgA 10 mg/dL. Which of the following additional signs is this patient most likely to exhibit?
a. contact dematitis
b. decreased phagocyte efficiency
c. immune complex disease
d. increased atopy
e. partial albinism
the serum level values in this case are all normal execpt for IgA which is low , patients of selective IgA deficiency which have an increased amount of atopic allergy it seems that because their inability to produce IgA they isotype to IgE more frequently
it can,t be contact dermatitis as it is a type od DTH ( delayed type hypersenstivity) depending on T helper cells , macrophages and cytotoxic lymphocytes and not increase in IgA deficiences
immune complex disease > it not corrected as it is realted with complement difiecncies
partial albinism >> have nothing to do with such case as it related to chediak higashi syndrome
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