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09-17-2015
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Extent of genetic counseling/probability questions?

Hi all,

So our school invests a few days pretty heavily on genetic counseling and related issues: for example we use Bayes' theorem to calculate that the probably a child will have a duchenne's MD assuming a 1/3 de novo mutation rate etc.

I was wondering if this is even remotely low yield or just completely untested? I'm not referring to basic carrier autodom/autorecessive etc nor am I talking about epidemiology (sensitivity,specificity), but more advanced mathematics (Bayes') to estimate the probably of a child having disease?

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