why large muscle mass causes lowee eGFR? - USMLE Forums
USMLE Forums Logo
USMLE Forums         Your Reliable USMLE Online Community     Members     Posts
USMLE Articles
Go Back   USMLE Forums > USMLE Step 1 Forum

USMLE Step 1 Forum USMLE Step 1 Discussion Forum: Let's talk about anything related to USMLE Step 1 exam

Thread Tools Search this Thread Display Modes
Old 10-24-2015
USMLE Forums Veteran
Steps History: Not yet
Posts: 213
Threads: 54
Thanked 59 Times in 44 Posts
Reputation: 69
Default why large muscle mass causes lowee eGFR?

Why.? Thanks
Reply With Quote Quick reply to this message

Old 10-25-2015
USMLE Forums Scout
Steps History: Step 1 Only
Posts: 23
Threads: 6
Thanked 12 Times in 7 Posts
Reputation: 22

GFR = ClearanceCR = Urine Cr x Urine Flow / Plasma Creat

Increased muscle mass ---> Increased Plasma Cr! Now if you do the old 24 hr method of collecting urine , you will see that Urine Cr increases too so it will be accurate .. But if you use the equations that you just put the Plasma Cr , they will obviously underestimate the GFR ( e.g bodybuilder may have 2.0 mg/ml serum Cr , which puts him in renal failure range , but actually he has no kideny problem at all)

Appreciate that this is the Calculated GFR only , in reality muscle mass by itself will not change the actual GFR

Last edited by tassosant13; 10-25-2015 at 03:16 AM. Reason: typo
Reply With Quote Quick reply to this message
The above post was thanked by:
rathoreprajay (03-09-2017)


Quick Reply

Register Now

In order to be able to post messages on the USMLE Forums forums, you must first register.
Please enter your desired user name, your email address and other required details in the form below.
User Name:
Please enter a password for your user account. Note that passwords are case-sensitive.
Confirm Password:
Email Address
Please enter a valid email address for yourself.
Email Address:
Medical School
Choose "---" if you don't want to tell. AMG for US & Canadian medical schools. IMG for all other medical schools.
USMLE Steps History
What steps finished! Example: 1+CK+CS+3 = Passed Step 1, Step 2 CK, Step 2 CS, and Step 3.

Choose "---" if you don't want to tell.

Favorite USMLE Books
What USMLE books you really think are useful. Leave blank if you don't want to tell.
Where you live. Leave blank if you don't want to tell.


Thread Tools Search this Thread
Search this Thread:

Advanced Search
Display Modes

Similar Threads
Thread Thread Starter Forum Replies Last Post
Large Plasma Cells in Peripheral Smear aknz USMLE Step 2 CK Forum 4 07-03-2017 01:36 AM
Large Spike in Gamma Region MedicalExaminer USMLE Step 1 Forum 13 10-28-2012 05:28 PM
A large four year old male? Evergreen USMLE Step 1 Forum 12 04-21-2012 06:50 AM
Achondroplasia; Large head or not! Mashee USMLE Step 1 Forum 8 06-17-2011 09:56 AM
Large Collection Of Medical Applications aktorque USMLE Step 1 Forum 0 11-14-2010 01:27 AM

Find Us on Facebook
Powered by vBulletin® Version 3.8.8
Copyright ©2000 - 2020, vBulletin Solutions, Inc.
vBulletin Security provided by vBSecurity v2.2.2 (Pro) - vBulletin Mods & Addons Copyright © 2020 DragonByte Technologies Ltd.

USMLE® & other trade marks belong to their respective owners, read full disclaimer
USMLE Forums created under Creative Commons 3.0 License. (2009-2019)