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  #1  
Old 04-15-2010
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Default Types of Collagen!

A 34-year-old man develops pulmonary hemorrhage and glomerulonephritis. Lung biopsy with immunofluorescence demonstrates IgG deposition along the basement membrane. These antibodies are most likely directed against which of the following types of collagen?

A. Type I
B. Type II
C. Type III
D. Type IV
E. Type X
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Old 04-15-2010
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this is Goodpasture syndrome i think. (pulm hemorrhage + glomerulonephritis with BM depositons)

so it should be collagen type IV.
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Old 04-15-2010
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I agree with seetal, BM is made from TypeIV collagen, so the IgG are directed against those in Goodpastures.
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Old 04-15-2010
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type 4 collagen!!!
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