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-   -   Why does neonatal respiratory distress syndrome cause METABOLIC acidosis and not respiratory acidosis? (https://www.usmle-forums.com/usmle-step-1-forum/243906-why-does-neonatal-respiratory-distress-syndrome-cause-metabolic-acidosis-not-respiratory-acidosis.html)

matxjos 02-08-2016 11:36 AM

Why does neonatal respiratory distress syndrome cause METABOLIC acidosis and not respiratory acidosis?
 
See title. Thanks!

docmoumi 02-08-2016 01:05 PM

I think there is both Respiratory and metabolic acidosis because of Hypoxemia and hypercarbia.

A late metabolic acidosis may develop in premature infants that receive high protein or amino acid intakes. This may be exacerbated by reduced reabsorption of bicarbonate from the proximal tubules and reduced new base formation by the kidneys of premature infants.

I found this online.

Any input from anyone appreciated

matxjos 02-08-2016 04:54 PM

Severe hypoxemia and systemic hypoperfusion result in decreased O2 delivery, anaerobic metabolism and subsequent lactic acidosis.

https://www.ucsfbenioffchildrens.org...als/25_RDS.pdf

Thanks!


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