D...........................?

 

D as I think

 

correct answer is E
hereditary glomerular disease-
alport's syndrome,autosomal dominant disease,x-linked recessive,autoantibodies to tipe IV collagen in GBM
no specific immunofluorescence or electron microscopic findings
sensorineural hearing loss and ocular abnormalitis
defective GBM synthesis due to mutations in a5 chain of collagen IV,associated form with diffuse leiomyomatosis has additional mutation in a6 chain
golgan rr 88, 404 pg
http://www.pathologyexpert.com/boards/onlinefiles/syndromes.htm
FA(2012)-84, 516 pg

 

F).................

 

F) is not one of answer of choice man!

 

the answer is C

 

i agree...its the alpha 3 chain of type 4 collagen

 

) was looking thru the answer choices to find type 4 collagen...sees all are type 4 collagen

 

Looks like you've found em! =)

 

Goljan RR says (3,4 or 5 ) , so which one is it?

 

A) Mutation in the gene for α1-chain of collagen type IV
B) Mutation in the gene for α2-chain of collagen type IV
C) Mutation in the gene for α3-chain of collagen type IV: Goodpasture's syndrome
D) Mutation in the gene for α4-chain of collagen type IV
E) Mutation in the gene for α5-chain of collagen type IV: Alport's syndrome: X-linked & Mutation genetic for α5-chain of collagen type IV(correct answer)

 

Lol, same guy with his bullshit questions. Every time I check these boards... without fail.

 

hey, whats the source of the question?

 

USMLERX:sleepy::sleepy::sleepy:

 

Actually i find his posts useful
I think the question stem is more important to refresh info on alports syndrome than the correct option

---
I am here: http://tapatalk.com/map.php?rlt2vz

 

Though these wouldn't be the type of Qs in actual exam(I pray they won't be :sorry

few af them help to know new things, refresh knowledge build connections and how worst could be the Qs.. He says few are from USMLE Rx so they are not made up either.. He at least cares to share ..

I just go through them take whatever I can and if they are way over my head I would be like whatever