ABO Rh incompatibility - USMLE Forums
USMLE Forums Logo
USMLE Forums         Your Reliable USMLE Online Community     Members     Posts
Home
USMLE Articles
USMLE News
USMLE Polls
USMLE Books
USMLE Apps
Go Back   USMLE Forums > USMLE Step 1 Forum

USMLE Step 1 Forum USMLE Step 1 Discussion Forum: Let's talk about anything related to USMLE Step 1 exam


Reply
 
Thread Tools Search this Thread Display Modes
  #1  
Old 06-04-2010
USMLE Forums Veteran
 
Steps History: 1 + CS
Posts: 209
Threads: 34
Thanked 119 Times in 52 Posts
Reputation: 149
Blood ABO Rh incompatibility

1-day-old neonate has hemolytic disease of the newborn. The parents are both Rh-positive, but IgG isohemagglutinins are found in the mother's blood. Which of the following parental blood types is most likely to cause this condition?

Mother blood group - Father blood group
(A) A - O
(B) AB - O
(C) B - A
(D) B - O
(E) O - AB
Reply With Quote Quick reply to this message



  #2  
Old 06-04-2010
USMLE Forums Guru
 
Steps History: ---
Posts: 487
Threads: 69
Thanked 341 Times in 163 Posts
Reputation: 361
Default E??

E) O AB....
as mother lack both A and B antigens...she can produce immunoglobulins if she comes in contact with fetal blood which can be of either A or B or AB.....
Reply With Quote Quick reply to this message
  #3  
Old 06-04-2010
USMLE Forums Veteran
 
Steps History: 1 + CS
Posts: 209
Threads: 34
Thanked 119 Times in 52 Posts
Reputation: 149
Default

yup true can u explain it in lilbit more detail i am little bit confused
Reply With Quote Quick reply to this message
 
  #4  
Old 06-04-2010
USMLE Forums Guru
 
Steps History: ---
Posts: 487
Threads: 69
Thanked 341 Times in 163 Posts
Reputation: 361
Default

this type of reaction occurs mostly in o positive pregnant women....normally BG O pregnant women hs both Anti A and Anti B antibodies but they r of IgM type so can not cross placenta....but she can produces IgG in response to A or B antigen from fetus....
here mother is O + so her genotype would be OO
and father is AB so genotype AB
so fetus will hv either OA or OB genotype...leading to either A or B antigens....
when mother comes in contact with fetal blood...she will produces IgG antibodies to either A antigen or B antigen....cross placenta..and lead to HDN....

hv a look at this site...
http://en.wikipedia.org/wiki/Hemolyt...e_newborn_(ABO)
Reply With Quote Quick reply to this message
  #5  
Old 06-04-2010
USMLE Forums Veteran
 
Steps History: 1 + CS
Posts: 209
Threads: 34
Thanked 119 Times in 52 Posts
Reputation: 149
Default

thanks alot got it
Reply With Quote Quick reply to this message
  #6  
Old 06-04-2010
USMLE Forums Scout
 
Steps History: 1+CK+CS
Posts: 86
Threads: 3
Thanked 14 Times in 14 Posts
Reputation: 24
Default

i'll go for E
Reply With Quote Quick reply to this message



Reply

Tags
Hematology-, Immunology-, Pediatrics-, Step-1-Questions

Quick Reply
Message:
Options

Register Now

In order to be able to post messages on the USMLE Forums forums, you must first register.
Please enter your desired user name, your email address and other required details in the form below.
User Name:
Password
Please enter a password for your user account. Note that passwords are case-sensitive.
Password:
Confirm Password:
Email Address
Please enter a valid email address for yourself.
Email Address:
Medical School
Choose "---" if you don't want to tell. AMG for US & Canadian medical schools. IMG for all other medical schools.
USMLE Steps History
What steps finished! Example: 1+CK+CS+3 = Passed Step 1, Step 2 CK, Step 2 CS, and Step 3.

Choose "---" if you don't want to tell.

Favorite USMLE Books
What USMLE books you really think are useful. Leave blank if you don't want to tell.
Location
Where you live. Leave blank if you don't want to tell.

Log-in


Thread Tools Search this Thread
Search this Thread:

Advanced Search
Display Modes


Similar Threads
Thread Thread Starter Forum Replies Last Post
ABO compatibility confusion wonder USMLE Step 1 Forum 4 02-14-2011 04:19 PM

Find Us on Facebook
Powered by vBulletin® Version 3.8.8
Copyright ©2000 - 2020, vBulletin Solutions, Inc.
vBulletin Security provided by vBSecurity v2.2.2 (Pro) - vBulletin Mods & Addons Copyright © 2020 DragonByte Technologies Ltd.

USMLE® & other trade marks belong to their respective owners, read full disclaimer
USMLE Forums created under Creative Commons 3.0 License. (2009-2019)