Comparison of Lactulose to Hodor (GOT)! - USMLE Forums
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Old 08-17-2016
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Default Comparison of Lactulose to Hodor (GOT)!

For some of you guys who are fans of GOT like me... there's some comparison that I just came up with.

So...lactulose is used as an osmotic laxative and in hepatic encephalopathy. It's MOA is by acidifying the colonic lumen, converting NH3 to NH4 in order to increase it's excretion and decrease toxicity.

Lactulose would be Hodor (it's sacrificing itself, letting being murdered by the colonic bacteria (white walkers) in order to be acidified and let NH3->NH4 (Bran) escape )

Hold the acid! Hold the acid! Holacid! Holactulid! Olactulos! Lactulose!
(Saddest scene in the history)
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