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-   -   How to memorize Lysosomal Storage Disorders! (https://www.usmle-forums.com/usmle-step-1-forum/3134-how-memorize-lysosomal-storage-disorders.html)

Androide89 06-28-2010 11:44 PM

How to memorize Lysosomal Storage Disorders!
 
how for God's sake do we memorize all the lysosomal storage diseases in First Aid, are they tested very often? and if so what exactly do they ask like the accumulated substrate or what?

mohsinkhan 06-29-2010 05:32 AM

Mnemonics dude

Peewee 06-29-2010 08:50 AM

Quote:

Originally Posted by Androide89 (Post 11314)
how the **** do we learn all the lysosomal storage diseases in first aid, are they tested very often? and if so what exactly do they ask like the accumulated substrate or what


You gotta hit them all the time. There is no easy way to do it. Repetition is the key with these.

You should know everything in FA about them. That includes the deficient enzyme and accumulated substrate. USMLE will ask you about that.

Other facts you should add in-

Gargoyle Face- Hurlers and Gauchers

Niemann Pick(S)- add the S to picks to then know its Sphingomyelinase/Sphingomyelin. There is Atrophy of frontal lobe and dementia, Zebra bodies and foam cells. HAS HEPATOMEGALY (Tay-Sachs does NOT)

Gauchers- Anything about a Macrophage, the looks, ect.. pick Gauchers. Erylmyer flask bones


As well the pay attention and know that X-link recessive is only Fabrys and Hunters. You may think this is moo, but when the real exam asks you something about this, poeple tend to forget due to nerves

rasheed 06-29-2010 09:48 AM

Lysosomal Storage Disorders Mnemonic
 
This thread may also help in memorizing, here's the link
http://www.usmle-forums.com/usmle-st...disorders.html

YoramFishke 06-29-2010 09:49 AM

They'll ask about the enzyme
 
Quote:

Originally Posted by Androide89 (Post 11314)
how for God's sake do we memorize all the lysosomal storage diseases in First Aid, are they tested very often? and if so what exactly do they ask like the accumulated substrate or what?

Yes, you have to memorize them by heart. There will be cases in your exam in which you have to diagnose the disorder then most probably they'll ask you which enzyme is deficient in this case.


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