USMLE Forums

USMLE Forums (https://www.usmle-forums.com/)
-   USMLE Step 1 Forum (https://www.usmle-forums.com/usmle-step-1-forum/)
-   -   Beta blockers in the treatment of Pheochromocytoma! (https://www.usmle-forums.com/usmle-step-1-forum/3307-beta-blockers-treatment-pheochromocytoma.html)

Zagaris 07-16-2010 07:29 AM

Beta blockers in the treatment of Pheochromocytoma!
 
I read that we should never give beta blockers in the treatment of pheochromocytoma.

I don't understand why :toosad:

Can anybody explain for me please

doc_study 07-16-2010 07:40 AM

Beta blockers in the treatment of Pheochromocytoma!
 
The adrenaline and nor-adrenaline released by adrenal medula act on both alpha & beta receptors. So, beta blockers alone will be of no help. Also, the unopposed alpha receptor stimulation will cause Increased vasoconstriction, further worsening the hypertention.
So best strategy is to give an alpha blocker before giving beta blockers, in a pt of pheochromocytoma.


Sent from my iPhone using Tapatalk

Zagaris 07-16-2010 07:57 AM

thanks
 
Quote:

Originally Posted by doc_study (Post 12074)
The adrenaline and nor-adrenaline released by adrenal medula act on both alpha & beta receptors. So, beta blockers alone will be of no help. Also, the unopposed alpha receptor stimulation will cause Increased vasoconstriction, further worsening the hypertention.
So best strategy is to give an alpha blocker before giving beta blockers, in a pt of pheochromocytoma.


Sent from my iPhone using Tapatalk

Thank you,
But then why beta blockers are enough in essential hypertension? :(

ecgram 07-16-2010 08:04 AM

pheochromocytoma is bec of the excessive production of catecholamines

but in essential HTN u dont know the cause of HTN ,its mostly idiopathic , so if u give just beta blockers it will help unlike in pheochromocytoma where u see effects of both alpha and beta receptors


All times are GMT -8. The time now is 03:42 PM.

Powered by vBulletin® Version 3.8.8
Copyright ©2000 - 2020, vBulletin Solutions, Inc.
vBulletin Security provided by vBSecurity v2.2.2 (Pro) - vBulletin Mods & Addons Copyright © 2020 DragonByte Technologies Ltd.

USMLE® & other trade marks belong to their respective owners, read full disclaimer
USMLE Forums created under Creative Commons 3.0 License. (2009-2019)