Y is dexamethasone supressed in cushin disease - USMLE Forums
USMLE Forums Logo
USMLE Forums         Your Reliable USMLE Online Community     Members     Posts
Home
USMLE Articles
USMLE News
USMLE Polls
USMLE Books
USMLE Apps
Go Back   USMLE Forums > USMLE Step 1 Forum

USMLE Step 1 Forum USMLE Step 1 Discussion Forum: Let's talk about anything related to USMLE Step 1 exam


Reply
 
Thread Tools Search this Thread Display Modes
  #1  
Old 01-26-2017
USMLE Forums Newbie
 
Steps History: Step 1 Only
Posts: 9
Threads: 7
Thanked 0 Times in 0 Posts
Reputation: 10
Default Y is dexamethasone supressed in cushin disease

Why is cortisol suppressed in dexamethason test in case of Cushing. Disease and why not for other causes of Cushing syndrome
Reply With Quote Quick reply to this message



  #2  
Old 01-26-2017
USMLE Forums Scout
 
Steps History: Step 1 Only
Posts: 46
Threads: 12
Thanked 33 Times in 17 Posts
Reputation: 43
Default

ANswer is given in first aid 2016 page-317
Cushing Ds refers to hypercortisolism because of increased ACTH secretion from pituitary.! Dexamethsone is potent synthetic glucocorticoid. High dose dexamethasone(8mg)will supress ACTH release from Pituitary by feedback inhibition and hence decreases cortisol level.
This feedback does not work when ACTH is produced outside pituitary e.g., ectopic source.
Hope this adresses your doubt.
Reply With Quote Quick reply to this message
The above post was thanked by:
Dr266 (01-27-2017)



Reply

Quick Reply
Message:
Options

Register Now

In order to be able to post messages on the USMLE Forums forums, you must first register.
Please enter your desired user name, your email address and other required details in the form below.
User Name:
Password
Please enter a password for your user account. Note that passwords are case-sensitive.
Password:
Confirm Password:
Email Address
Please enter a valid email address for yourself.
Email Address:
Medical School
Choose "---" if you don't want to tell. AMG for US & Canadian medical schools. IMG for all other medical schools.
USMLE Steps History
What steps finished! Example: 1+CK+CS+3 = Passed Step 1, Step 2 CK, Step 2 CS, and Step 3.

Choose "---" if you don't want to tell.

Favorite USMLE Books
What USMLE books you really think are useful. Leave blank if you don't want to tell.
Location
Where you live. Leave blank if you don't want to tell.

Log-in


Thread Tools Search this Thread
Search this Thread:

Advanced Search
Display Modes


Similar Threads
Thread Thread Starter Forum Replies Last Post
Dexamethasone Suppression Test steroidmd USMLE Step 1 Classic Clues 5 02-16-2017 08:59 PM
Dexamethasone Suppression Test PassIton USMLE Step 2 CK Forum 0 03-19-2013 03:55 PM
Dexamethasone Suppression Test donofitaly USMLE Step 1 Forum 6 09-05-2012 01:14 PM
The use of Dexamethasone in bacterial meningitis rasheed USMLE Step 2 CK Bits & Pieces 1 06-12-2010 07:10 PM
Dexamethasone Suppression! hippocampus USMLE Step 1 Forum 4 01-13-2010 02:58 PM

Find Us on Facebook
Powered by vBulletin® Version 3.8.8
Copyright ©2000 - 2020, vBulletin Solutions, Inc.
vBulletin Security provided by vBSecurity v2.2.2 (Pro) - vBulletin Mods & Addons Copyright © 2020 DragonByte Technologies Ltd.

USMLE® & other trade marks belong to their respective owners, read full disclaimer
USMLE Forums created under Creative Commons 3.0 License. (2009-2019)