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Old 07-28-2010
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Drug Cell Wall Inhibitors

Penicillins and Cephalosporins are Cell Wall Inhibitors so are effective against Gram Postive bacteria...

Vancomycin is also a cell wall inhibitor so active against gram + but not against gram -

Then how come penicillin is the DOC in Meningococcemia and extended spectrum penicillins work against Gram negative organisms when Vancomycin does not ?
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Old 07-28-2010
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Quote:
Originally Posted by anoop_1198 View Post
Penicillins ....
Vancomycin is also a cell wall inhibitor so active against gram + but not against gram -
Them how come penicillin is the DOC in Meningococcemia and extended spectrum penicillins work against Gram negative organisms when Vancomycin does not ?
Don't mix penicillins with vancomycin they both are Inhibitors of cell wall synthesis but they have different structure and mechanism of action.
Vancomycin is not active against gram (-). Penicillin not only effective in Gram(+) it also effective against some Gram (-) for example against famous Neisseria
I think you will remember this picture long time (btw her sister or brother causes the meningococcemia)

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hiratamkeen (07-04-2011)



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