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-   -   Revise antibiotic MOA with me . (https://www.usmle-forums.com/usmle-step-1-forum/37801-revise-antibiotic-moa-me.html)

koyi 11-02-2012 09:05 AM

Revise antibiotic MOA with me .
 
A 27-year-old woman is admitted to the hospital with complaints of lower abdominal pain, mucoid vaginal discharge, nausea, and vomiting for three days. She denies skin and mucosal lesions or dysuria. Her last menstrual period was two weeks ago. Her temperature is 101.4 F. She has tenderness in the right lower abdominal quadrant. The pelvic examination shows bilateral adnexal tenderness and pain with cervical motion. There is a cloudy mucoid discharge from the cervix. The pregnancy test is negative. Gram stain of the cervical discharge shows whites cells with no organisms, and the culture is pending. The patient is started on appropriate antibiotics . what are the mechanism of actions of possible antibiotics given to this young lady ?

venky2600 11-02-2012 09:53 AM

i'm thinking it as chlamydia----PID..

treated by macrolides(protein synthesis inhibition)------------

thanks:)

alice 11-02-2012 10:01 AM

Isn't doxycycline DOC for chlamydia ??

koyi 11-02-2012 10:07 AM

macrolide (esp Azithromycin ) is DOC for clamydia . doxcycline can be applicable too , but isnt 1st line for clamydia

koyi 11-02-2012 10:11 AM

Quote:

Originally Posted by venky2600 (Post 159223)
i'm thinking it as chlamydia----PID..

treated by macrolides(protein synthesis inhibition)------------

thanks:)

yeap , ryt dr Venky 2006 . but one question , if we find gonorrhea PID , we have to treat both gono PID and chlamyd PID , coz of high risk of coinfection . but what about get chlamyd PID , is it necessary treat gono PID too ? is this rule applicable in both direction ? thanks

venky2600 11-02-2012 10:14 AM

Quote:

Originally Posted by koyi (Post 159231)
yeap , ryt dr Venky 2006 . but one question , if we find gonorrhea PID , we have to treat both gono PID and chlamyd PID , coz of high risk of coinfection . but what about get chlamyd PID , is it necessary treat gono PID too ? is this rule applicable in both direction ? thanks

haha...i never thought of that way:p.......but i think it dont apply coz...gonorrhea can be stained well IMO....

koyi 11-02-2012 10:18 AM

Quote:

Originally Posted by venky2600 (Post 159234)
haha...i never thought of that way:p.......but i think it dont apply coz...gonorrhea can be stained well IMO....

but what do u understand by HIGH RISK OF COINFECTION as many Sources (books , qbank or video lectures ) say abt these two bugs . because real i just memorize it but ddnt get weel the sentence Coinfection in relation to these two bugs . help me please

venky2600 11-02-2012 10:25 AM

Quote:

Originally Posted by koyi (Post 159236)
but what do u understand by HIGH RISK OF COINFECTION as many Sources (books , qbank or video lectures ) say abt these two bugs . because real i just memorize it but ddnt get weel the sentence Coinfection in relation to these two bugs . help me please

may be you're right i guess...if we treat only one the other organism may be more susceptible to cause infection..........so both should be treated......

i'm not sure either:notsure:


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