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-   -   Growth Hormone and Prolactin mode of action. (https://www.usmle-forums.com/usmle-step-1-forum/4164-growth-hormone-prolactin-mode-action.html)

donofitaly 09-23-2010 01:09 AM

Growth Hormone and Prolactin mode of action.
 
Do GH and Prolactin use Tyrosine Kinase pathway for their action? In FA2010 Errata it was pointed as a mistake but most other sources say it is the mode of action. Please help.

ashishkabir 09-23-2010 06:20 AM

Yeah - I think it uses a JAK-STAT pathway - here:

http://www.ncbi.nlm.nih.gov/pubmed/8815791



What is a JAK-STAT pathway you ask? Here you go :)

http://en.wikipedia.org/wiki/JAK-STAT_signaling_pathway



I'm not sure how much of this detail is essential - but here it is anyway...

Syndromic 09-23-2010 02:23 PM

Found a related great talk
 
Guys, have a look at this great thread
http://www.usmle-forums.com/usmle-st...signaling.html


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