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Old 10-06-2010
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Smile Combination question.

Following is the question where i have combined three connected questions together and made this one up. Hope its correctly framed.

Question -

A 35-year-old patient is seen in your office for hypertension. On exam, he appears obese with weight particularly located on his trunk and face, with sparing of his limbs. He has lipodystrophy of his neck and purple striae around his legs. He acknowledges muscle weakness and says he has an inability to maintain erection during intercourse. He denies taking any medications. If the patient above had a history of cancer, where may the cancer be located?

A - Bone
B - Liver
C - Lung
D - Medulla
E - Small Intestine
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Old 10-06-2010
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C - Lung

Small cell carcinoma of the lung releasing ACTH and causing cushing syndrome, although he's young for such cancer!
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Old 10-06-2010
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it must be the small cell carcinoma of lung....
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Old 10-06-2010
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Yup - ACTH from small cell lung cancer causing Cushings because of Cortisol rls from Adrenal Cortex Fasiculata layer. I think we'd use a Dexamethasone suppression test to verify right?
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Old 10-06-2010
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Yep, all of you are right on this one.

Guess its not as difficult as i thought it would be when i framed it. :P
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