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Old 10-23-2010
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Question The most common cause of death in Acromegaly?

what is the most common cause of death in acromegaly patient?
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Cardiomyopathy leading to heart failure. Everything gets bigger in Acromegaly because of stimulation by Growth Hormone. I think Goljan discussed this.
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Old 10-23-2010
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yeah that's right...the cause of death is heart failure from cardiomyopathy~
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Old 10-23-2010
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Default Difference between Acromegaly & Gigantism

Interesting thing about acromegaly that I learned today: both acromegaly and gigantism are caused by too much growth hormone. The difference between them is at what point in the development the excess growth hormone occurs.
If it's during infancy or childhood before fusion of the epiphyseal growth plates, you get gigantism, which is proportional overgrowth.
If it's during adulthood when the growth plates are already fused, you get acromegaly, which is disproportional overgrowth i.e. you get wider but not taller.
Leading cause of death in both gigantism and acromegaly is cardiac defects (Andre the Giant died from CHF).
Fun fact: Arnold Schwarzenegger has acromegaly because he took growth hormones when he was a body builder. Note the widening of the lower jaw (resulting in gaps between his teeth) and large hands!
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Old 10-24-2010
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Quote:
Originally Posted by heights View Post
Interesting thing about acromegaly that I learned today: both acromegaly and gigantism are caused by too much growth hormone. The difference between them is at what point in the development the excess growth hormone occurs.
If it's during infancy or childhood before fusion of the epiphyseal growth plates, you get gigantism, which is proportional overgrowth.
If it's during adulthood when the growth plates are already fused, you get acromegaly, which is disproportional overgrowth i.e. you get wider but not taller.
Leading cause of death in both gigantism and acromegaly is cardiac defects (Andre the Giant died from CHF).
Fun fact: Arnold Schwarzenegger has acromegaly because he took growth hormones when he was a body builder. Note the widening of the lower jaw (resulting in gaps between his teeth) and large hands!
Seems like you just started to listen to Goljan. :P
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Quote:
Originally Posted by donofitaly View Post
Seems like you just started to listen to Goljan. :P
I did! He is so funny, things like that help me remember stuff.
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