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mtoi 10-29-2010 03:36 PM

Temporal Arteritis Pathology!
68 yo white male experiences headaches and recent vision deterioration improves dramatically with predinisone. Which of the following pathological processes define temporal arteritis?

A homogenous acellular thickening of arteriolar walls
B granulomatous inflammation of media
C tansmural inflammation with fibrinoid necrosis
D onion-like concentric thickening of arteriolar walls

Haisook 10-29-2010 03:40 PM

B granulomatous inflammation of media

Btw, also Takayasu arteritis shares the same pathology, but expect the patient to be a young to middle-aged Asian woman, with weak pulses in the upper extremities. Both are associated with high ESR.

mtoi 10-29-2010 03:44 PM

Temporal arteritis is the most common form of systemic vasculitis in adults.
It predominantly involves medium to smaller branches of carotid artery, especially temporal.
Medial granulomas may also be seen in takayasu arteritis which typically affects aortic arch

you folks are awesome

pakbrain 10-29-2010 06:17 PM

Temporal arteritis also known as Giant cell arteritis is chronic granulamatous inflamation of mostly large arteries such as temporal artery in head , vertebral/opthalmic artery and aorta , on microscopic appearance there is nodular intimal thickening of involved arterial segments and granulamtous inflammation within the media

In takayasu falls in the same category except it involves persons younger than age 50 while its reverse in case of temporal arteritis

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