Hey,
I've been trying to get my head around why loss of HCO3 from diarrhoea or type 2 RTA leads to a non-anion gap acidosis, when the equation to calculate anion gap is:
[Na + K] - [Cl + HCO3]
I know that I've missed out a bit of physiology knowledge that would make it make sense but at the moment I'm just wondering that shouldn't a lower level of bicarb lead to a bigger number of the anion gap?
Thanks for any help.
I've been trying to get my head around why loss of HCO3 from diarrhoea or type 2 RTA leads to a non-anion gap acidosis, when the equation to calculate anion gap is:
[Na + K] - [Cl + HCO3]
I know that I've missed out a bit of physiology knowledge that would make it make sense but at the moment I'm just wondering that shouldn't a lower level of bicarb lead to a bigger number of the anion gap?
Thanks for any help.