Thalassemia Minor versus Thalassemia Trait - USMLE Forums
USMLE Forums Logo
USMLE Forums         Your Reliable USMLE Online Community     Members     Posts
USMLE Articles
Go Back   USMLE Forums > USMLE Step 2 CK Forum

USMLE Step 2 CK Forum USMLE Step 2 CK Discussion Forum: Let's talk about anything related to USMLE Step 2 CK exam

Thread Tools Search this Thread Display Modes
Old 11-06-2011
USMLE Forums Newbie
Steps History: CS Only
Posts: 3
Threads: 3
Thanked 0 Times in 0 Posts
Reputation: 10
RBC Thalassemia Minor versus Thalassemia Trait

what is Thalassemia trait?
Thalassemia minor causes mild anemia and microcytosis, but how it can cause this symptoms if the person just carries the gene?

Reply With Quote Quick reply to this message

Old 11-06-2011
USMLE Forums Addict
Steps History: Not yet
Posts: 129
Threads: 18
Thanked 203 Times in 63 Posts
Reputation: 213

Hmm... Well actually it depends on how many deleted genes you've got..
There are 4 alPha genes in normal individuals. and symptoms are based on the number of those genes beong deleted.
if you have one gene or 4 genes deleted you normally dont see those patients in practice cuz the first patient wont have any symptoms which is alled TRAIT and the second patient is dead. two genes deleted will give you thalasemia minor and 3 genes deleted will give moderetly severe hemolytic anemia.
i hope this clarify the point .
Reply With Quote Quick reply to this message
The above post was thanked by:
LatinGeorge (12-21-2011), N Nur (11-07-2011)


Hematology-, Pediatrics-

Quick Reply

Register Now

In order to be able to post messages on the USMLE Forums forums, you must first register.
Please enter your desired user name, your email address and other required details in the form below.
User Name:
Please enter a password for your user account. Note that passwords are case-sensitive.
Confirm Password:
Email Address
Please enter a valid email address for yourself.
Email Address:
Medical School
Choose "---" if you don't want to tell. AMG for US & Canadian medical schools. IMG for all other medical schools.
USMLE Steps History
What steps finished! Example: 1+CK+CS+3 = Passed Step 1, Step 2 CK, Step 2 CS, and Step 3.

Choose "---" if you don't want to tell.

Favorite USMLE Books
What USMLE books you really think are useful. Leave blank if you don't want to tell.
Where you live. Leave blank if you don't want to tell.


Thread Tools Search this Thread
Search this Thread:

Advanced Search
Display Modes

Similar Threads
Thread Thread Starter Forum Replies Last Post
The cause of jaundice in Thalassemia major usmleman2020 USMLE Step 1 Forum 8 03-25-2012 02:39 PM
some confusion regarding thalassemia.. struggle USMLE Step 1 Forum 6 08-19-2011 06:50 AM
Thalassemia differentiation usluipek USMLE Step 1 Forum 2 05-31-2011 01:32 PM
Do we have high reticulocyte count in Thalassemia Major? hana USMLE Step 1 Forum 6 01-23-2011 08:38 PM
Alfa Thalassemia Trait Mnemonic lee-usmle USMLE Step 1 Mnemonics 0 08-29-2009 12:53 PM

Find Us on Facebook
Powered by vBulletin® Version 3.8.8
Copyright ©2000 - 2020, vBulletin Solutions, Inc.
vBulletin Security provided by vBSecurity v2.2.2 (Pro) - vBulletin Mods & Addons Copyright © 2020 DragonByte Technologies Ltd.

USMLE® & other trade marks belong to their respective owners, read full disclaimer
USMLE Forums created under Creative Commons 3.0 License. (2009-2019)