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Old 09-07-2012
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Neuro Brain tumor

A 57-year-old man complains of worsening headache, nausea, and vomiting for 2 months. On examination, he is lethargic, confused, and has right-sided weakness. While waiting for a computed tomography (CT) scan, he develops
status epilepticus, suffers cardiorespiratory arrest, and dies. His brain at autopsy is shown in Figure 1-4. Which of the following is the most likely diagnosis?

(A) glioma
(B) meningioma
(C) craniopharyngioma
(D) pituitary adenoma
(E) acoustic neuroma



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Old 09-07-2012
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Answer is (A) glioma.

This is glioma with hemorrhage inside, producing cerebral edema and transtentorial herniation.
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Old 09-07-2012
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yes looks like A ........ other option dont seem to be killer .......
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Old 09-07-2012
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Is it only me, can't see any pictures.

I would also go for option (A) glioma,
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A. Glioma!
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A for sure.........necrotic and haemorrhagic lesion in the cortex
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A glioma, necrotic like everyone else said

Mengiomas are one of the 4 tumors that could have psammoma bodies (meningioma, epithelial ovarian, thyroid papillary, and mesothelioma)
Craniopharyngioma is rich in cholesterol (all of this is step 1 knowledge)
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Answer (A) The autopsy specimen illustrated in Figure contains a large, multicolored, irregular tumor invading the left hemisphere. There is hemorrhage,necrosis, and surrounding edema. The clinical and pathologic findings are most compatible with a diagnosis of malignant glioma (astrocytoma). Glioma is a highly malignant tumor of astrocytic cells and is the most common primary brain tumor. It infiltrates widely, often involving multiple lobes, as well as the opposite hemisphere via the corpus callosum. Prognosis is poor, with an average survival time of 6 months after diagnosis. Meningiomas are benign primary brain tumors that are usually slow growing and occur outside of the hemispheres, where they are well encapsulated and compressed but do not
invade brain tissue. Craniopharyngiomas arise from remnants of Rathke’s pouch (the craniopharyngeal anlage). They are usually benign, well encapsulated, and found in or near the sella turcica. Acoustic neuromas arise from the root of the eighth cranial nerve in the cerebellopontine angle. Like meningiomas, they are encapsulated and compressed rather than invade brain
substance.
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