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Old 09-07-2012
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Arrow Gyrus Daily Questions; Pediatrics #21

You are seeing a healthy, full-term infant just after delivery. The mother plans on breast-feeding the baby and asks you how long immunity transferred to the baby from the pregnancy would be present. When does passively transferred maternal IgG antibody reach a nadir?


(A) 1–2 months
(B) 3–6 months
(C) 12–18 months
(D) 18–24 months
(E) 24 months
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Old 09-08-2012
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ans B..........
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Quote:
Originally Posted by cingulate.gyrus View Post
You are seeing a healthy, full-term infant just after delivery. The mother plans on breast-feeding the baby and asks you how long immunity transferred to the baby from the pregnancy would be present. When does passively transferred maternal IgG antibody reach a nadir?


(A) 1–2 months
(B) 3–6 months
(C) 12–18 months
(D) 18–24 months
(E) 24 months
B.) IgG goes down 6 mo after birth
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B

Remember thAt all B cell deficiencies start to manifest after 6months of age which is when maternal Ig's wean off
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Answer is B

Passively transferred maternal IgG decreases commensurate with the half-life, which is approximately 30 days. Therefore the nadir occurs in infants at the age of 3–6 months

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