Gyrus Daily Questions; Pediatrics #39 - USMLE Forums
USMLE Forums Logo
USMLE Forums         Your Reliable USMLE Online Community     Members     Posts
Home
USMLE Articles
USMLE News
USMLE Polls
USMLE Books
USMLE Apps
Go Back   USMLE Forums > USMLE Step 2 CK Forum

USMLE Step 2 CK Forum USMLE Step 2 CK Discussion Forum: Let's talk about anything related to USMLE Step 2 CK exam


Reply
 
Thread Tools Search this Thread Display Modes
  #1  
Old 09-09-2012
USMLE Forums Master
 
Steps History: 1+CK+CS
Posts: 720
Threads: 217
Thanked 569 Times in 317 Posts
Reputation: 579
Arrow Gyrus Daily Questions; Pediatrics #39

A 15 year old female presented to the emergency department with history of recurrent epistaxis, hematurua and hematochezia.There was a history of profuse bleeding from the umbilicus stump at birth.Previous investigations revealed normal prothrombin time, activated partial thromboplastin time,thrombin time and fibrinofen levels.Her platelet counts as well as platelet function tests were normal but urea lysis test was positive.Which one of the following clotting factor is most likely to be deficient ?

A. Factor X.
b. Factor XI
C. Factor XII
d. Factor XIII
Reply With Quote Quick reply to this message
The above post was thanked by:
step1an (09-09-2012)



  #2  
Old 09-09-2012
Hitman's Avatar
USMLE Forums Master
 
Steps History: Not yet
Posts: 928
Threads: 17
Thanked 576 Times in 400 Posts
Reputation: 586
Default

ans .......D .......... didnt know about this had to search it .........
Reply With Quote Quick reply to this message
The above post was thanked by:
cingulate.gyrus (09-09-2012)
  #3  
Old 09-09-2012
Anders's Avatar
USMLE Forums Veteran
 
Steps History: 1+CK+CS
Posts: 289
Threads: 7
Thanked 149 Times in 116 Posts
Reputation: 159
Default

Quote:
Originally Posted by cingulate.gyrus View Post
A 15 year old female presented to the emergency department with history of recurrent epistaxis, hematurua and hematochezia.There was a history of profuse bleeding from the umbilicus stump at birth.Previous investigations revealed normal prothrombin time, activated partial thromboplastin time,thrombin time and fibrinofen levels.Her platelet counts as well as platelet function tests were normal but urea lysis test was positive.Which one of the following clotting factor is most likely to be deficient ?

A. Factor X.
b. Factor XI
C. Factor XII
d. Factor XIII
This is a new concept to me, so i did the search. I got the following:
Factor XIII(Fibrin stablizing factor) helps to stablize the clot after itīs formed. but if itīs absent cause dissolution of the clot and result in failure of haemostasis.
The first step in detection is a screening test know as urea lysis test in which the pt. sample in incubated with thrombin and Ca to form clot then place in a media containing 5M of urea and incubated for 24 hour, it if dissolves it mean XIII deficiency .
then to confirmt he deficiency then need quantitative assay of XIII.

So, the answer would be D
Reply With Quote Quick reply to this message
The above post was thanked by:
cingulate.gyrus (09-09-2012), K06100 (09-09-2012)
 
  #4  
Old 09-09-2012
USMLE Forums Master
 
Steps History: 1+CK+CS
Posts: 1,866
Threads: 149
Thanked 2,249 Times in 1,096 Posts
Reputation: 2269
Default

fibrin stabilizing factor>>> the Preserver (Vishnu) deficiency (Conrad Fischer lecture)

Thrombin>>> Brahma (the creator)

Plasmin
>>> Shiva (the destroyer)

Last edited by Novobiocin; 09-09-2012 at 05:12 PM.
Reply With Quote Quick reply to this message
The above post was thanked by:
cingulate.gyrus (09-09-2012), K06100 (09-10-2012)
  #5  
Old 09-09-2012
USMLE Forums Master
 
Steps History: 1+CK+CS
Posts: 720
Threads: 217
Thanked 569 Times in 317 Posts
Reputation: 579
Default

Quote:
Originally Posted by Novobiocin View Post
fibrin stabilizing factor>>> the Preserver (Vishnu) deficiency (Conrad Fischer lecture)

Thrombin>>> Brahma (the creator)

Plasmin
>>> Shiva (the destroyer)

Bahooth Achaa...............Bahooth Achaaa.....Sathyam Sivam ..Sundaram.... Fischer..!!!

Last edited by cingulate.gyrus; 09-09-2012 at 09:20 PM. Reason: adding some thing
Reply With Quote Quick reply to this message
The above post was thanked by:
K06100 (09-10-2012)



Reply

Tags
Pediatrics-, Step-2-Questions

Quick Reply
Message:
Options

Register Now

In order to be able to post messages on the USMLE Forums forums, you must first register.
Please enter your desired user name, your email address and other required details in the form below.
User Name:
Password
Please enter a password for your user account. Note that passwords are case-sensitive.
Password:
Confirm Password:
Email Address
Please enter a valid email address for yourself.
Email Address:
Medical School
Choose "---" if you don't want to tell. AMG for US & Canadian medical schools. IMG for all other medical schools.
USMLE Steps History
What steps finished! Example: 1+CK+CS+3 = Passed Step 1, Step 2 CK, Step 2 CS, and Step 3.

Choose "---" if you don't want to tell.

Favorite USMLE Books
What USMLE books you really think are useful. Leave blank if you don't want to tell.
Location
Where you live. Leave blank if you don't want to tell.

Log-in


Thread Tools Search this Thread
Search this Thread:

Advanced Search
Display Modes


Similar Threads
Thread Thread Starter Forum Replies Last Post
Gyrus Daily Questions; Pediatrics #15 cingulate.gyrus USMLE Step 2 CK Forum 5 09-08-2012 08:51 AM
Gyrus Daily Questions; Pediatrics #17 cingulate.gyrus USMLE Step 2 CK Forum 9 09-07-2012 10:15 PM
Gyrus Daily Questions; Pediatrics #16 cingulate.gyrus USMLE Step 2 CK Forum 5 09-07-2012 08:54 PM
Gyrus Daily Questions; Pediatrics #6 cingulate.gyrus USMLE Step 2 CK Forum 5 09-07-2012 05:36 AM
Gyrus Daily Questions; Pediatrics #8 cingulate.gyrus USMLE Step 2 CK Forum 8 09-06-2012 12:06 PM

Find Us on Facebook
Powered by vBulletin® Version 3.8.8
Copyright ©2000 - 2020, vBulletin Solutions, Inc.
vBulletin Security provided by vBSecurity v2.2.2 (Pro) - vBulletin Mods & Addons Copyright © 2020 DragonByte Technologies Ltd.

USMLE® & other trade marks belong to their respective owners, read full disclaimer
USMLE Forums created under Creative Commons 3.0 License. (2009-2019)