Hepatitis B Positive Pregnant Woman

[step_enhancer]

A woman in the first trimester is found positive Hepatitis B surface antigen and HBeAg is also found to be positive. what will be the next step in management ??

I read this in MTB 3, what will be the next step ?

[Anders]

HBIG

Avoid any invasive procedure

Immunization & HBIG to the neonate

[XpaezX]

Next step is to chill and after the baby is born immediately give him first shot of HBV vaccine and HBIG, the mother depending on her evolution if she developed Ab-HBs then she has immunity, if she went into chronicity you can treat her with either interferon OR lamivudine (in hepatitis B you only give one drug, it is in hepatitis C in which you give 2)

[Novobiocin]

Pregnant Hepatitis B carriers should be advised to

• Obtain vaccination against hepatitis viruses A as indicated.
• Abstain form alcohol use
• Avoid hepatotoxic drugs such as acetaminophen (Tylenol) that may worsen liver damage.
• Not donate blood, body organs, or other tissue.
• Not share any personal items that may have blood on them (e.g., toothbrushes and razors).
• Inform the infant’s pediatrician, OB/GYN, and labor staff that they are a hepatitis B carrier.
• Make sure their baby receives hepatitis B vaccine at birth, one month, and six months of age as well as H-BIG at birth.
• Be seen at least annualy by their regular medical doctor.
• Discuss the risk for transmission with their partner and discuss the need for counseling and testing
• Liver function testing is recommended for women who test positive for HBsAg

[tara7]

There is currently no alternative treatment available for Hepatitis b and c in pregnancy or to minimize the risk of the baby catching hepatitis B at birth. The hepatitis B vaccine alone is not as effective as giving both the hepatitis B vaccine and immunoglobulin. In the weeks before delivery, women with very high levels of hepatitis B virus in their blood may be offered daily treatment with an antiviral medicine to reduce the level of virus in their blood at delivery. This treatment does not replace the need for their babies to receive immunoglobulin and vaccinations.

[dailyrx]

Here's a great resource for understanding Hepatitis treatment: RxWiki provides drug information, written by pharmacists. You can learn more about Hepsera, a treatment for hepatitis b here: http://www.rxwiki.com/hepsera